Inference Optimization
46 guides in this topicOnce a model is deployed, the real work starts: making it fast and cheap enough to run in production. This is the biggest cluster on the blog because inference optimization has the most moving parts: KV cache management (PagedAttention, LMCache, NVMe offloading), quantization formats (FP8, FP4, NVFP4 versus MXFP4, AWQ), speculative decoding (EAGLE-3, DFlash, multi-token prediction), and structural changes like prefill-decode disaggregation and attention variants built for long context (Ring Attention, log-linear attention, DeepSeek Sparse Attention).
Every technique here comes with a number: how much VRAM it saves, how much it speeds up time-to-first-token, or how it changes cost per million tokens, because "faster" without a benchmark isn't useful when you're deciding what to actually implement.
The pillar post, GPU Memory Requirements for LLMs, is the foundation the rest of this cluster builds on: the VRAM math for weights, KV cache, and quantization across model sizes from 7B to 744B, and how to match a model to the cheapest GPU that actually runs it. Start there if inference is running but you don't yet know where the bottleneck is. If you already know it's the KV cache or the attention kernel, the specific posts in this cluster go deep on exactly that.
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All Inference Optimization Guides

Best Open-Source LLMs to Self-Host in 2026: VRAM Tier Guide
Jun 23, 2026
Context Engineering for Production AI Agents: KV Cache, Prefix Caching, and Long-Context GPU Economics (2026 Guide)
Jun 17, 2026
GPU Cold Start on Serverless LLM Inference: 4 Fixes That Actually Work (2026)
Jun 15, 2026
NVFP4 vs MXFP4: 4-Bit Quantization Format Decision Guide for LLM Inference (2026)
Jun 13, 2026
SubQ 1M-Preview: What the First Subquadratic LLM Means for GPU Cloud Inference (2026 Guide)
Jun 8, 2026
NVIDIA ICMSP Explained: KV Cache NVMe Offload, 5x Inference Gains, and Setup Guide (2026)
Jun 6, 2026
DeepSeek Sparse Attention on GPU Cloud: Deploy Long-Context LLMs at 80% Less Compute (2026 Guide)
Jun 5, 2026
Multi-Token Prediction on GPU Cloud: Deploy MTP LLMs for 2-3x Faster Inference (2026)
Jun 5, 2026
Eagle-3 Speculative Decoding on GPU Cloud: 3-4x Faster LLM Inference (2026)
May 30, 2026
Test-Time Training on GPU Cloud: Deploy TTT Layers for Adaptive LLM Inference Without Retraining (2026 Guide)
May 29, 2026
NVIDIA TensorRT Model Optimizer (ModelOpt): FP8, INT4, and FP4 Quantization Guide (2026)
May 28, 2026
FlashAttention 2 vs FlashAttention 3: H100 and H200 Speedups, FP8 Support, and Migration Guide (2026)
May 25, 2026
What is FP8 Quantization? AI Inference Performance, Accuracy, and Hardware Support Explained (2026)
May 23, 2026
NVIDIA Transformer Engine: FP8 Mixed Precision on H100 and H200 (Setup, Code, Benchmarks 2026)
May 22, 2026
GPU Goodput Engineering: Why AI Clusters Sit at 5% Utilization and How to Fix It (2026)
May 19, 2026
Sleep-Time Compute on GPU Cloud: Pre-Compute Long-Lived Context for 5x Lower Query Latency
May 19, 2026
LLM Pruning on GPU Cloud: SparseGPT and Wanda for 50% Model Compression Without Retraining (2026)
May 17, 2026
LLM Inference SLO Engineering: TTFT, ITL, and P99 Latency Budgets for Production AI (2026)
May 15, 2026
Ring Attention and Tree Attention on GPU Cloud: Sequence Parallelism for 10M-Token LLM Inference (2026 Guide)
May 14, 2026
Deploy xLSTM and RWKV-7 on GPU Cloud: Linear-Attention Alternatives for Million-Token Context Inference (2026)
May 6, 2026
Batch LLM Inference on GPU Cloud: Offline Processing Pipelines for 10x Lower Cost vs Real-Time Serving (2026 Guide)
Apr 24, 2026
Deploy FLUX.2 on GPU Cloud: Production Image Generation Setup Guide (2026)
Apr 19, 2026
GPU Cost Per Token: Benchmark 7 Major LLMs Across GPU Types in 2026
Apr 18, 2026
DFlash on GPU Cloud: 6x Faster LLM Inference with Block Diffusion Speculative Decoding (2026)
Apr 14, 2026
MXFP4 Quantization on GPU Cloud: Deploy LLMs at 4-Bit Precision (2026)
Apr 14, 2026
AI's Memory Wall Problem: Why More GPUs Don't Fix Inference Latency (2026)
Apr 11, 2026
GGUF Dynamic Quantization on GPU Cloud: Deploy LLMs 50% Cheaper with Unsloth Dynamic 2.0
Apr 9, 2026
Google TurboQuant: 6x KV Cache Compression for LLM Inference
Apr 8, 2026
AWQ Quantization Guide: Deploy LLMs at Half the GPU Cost (2026)
Apr 7, 2026
What Is Inference Engineering? The 2026 GPU Cloud Guide
Apr 7, 2026
Inference-Time Compute Scaling on GPU Cloud: Allocate More GPU to Think Harder, Not Train Bigger (2026)
Apr 7, 2026
LLM Serving Optimization: Continuous Batching, PagedAttention, and Chunked Prefill on H100 (2026)
Apr 4, 2026
NVIDIA NIXL and Disaggregated Inference: Move KV Caches Across GPUs at Wire Speed
Apr 3, 2026
Prefill-Decode Disaggregation on GPU Cloud: Split LLM Inference for 2x Throughput (2026 Guide)
Apr 3, 2026
NVMe KV Cache Offloading for LLM Inference: Serve 10x More Users on the Same GPU (2026)
Apr 1, 2026
Reduce Reasoning Model Inference Costs by 8x: GPU Optimization Guide (2026)
Apr 1, 2026
Why Your LLM Inference Is Slow (And How to Fix It)
Mar 29, 2026
KV Cache Optimization: Serve 10x More Users on the Same GPU (2026)
Mar 28, 2026
LoRA Multi-Adapter Serving: Fine-Tune Once, Serve 100 Customers on One GPU
Mar 28, 2026
Speculative Decoding Production Guide: 2-5x Faster LLM Inference on GPU Cloud
Mar 26, 2026
Deploy Wan 2.1/2.2 for AI Video: GPU Requirements and ComfyUI Setup
Mar 18, 2026
FP4 Quantization on Blackwell GPUs: Throughput, Cost, and When It's Worth It
Mar 15, 2026
How to Run LLMs Locally with Ollama: GPU-Accelerated Setup Guide
Nov 3, 2025Try It on Real GPUs
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